Montazeri A, Goshtasebi A, Vahdaninia M, Gandek B (2005) The Short Form Health Survey (SF-36): translation and validation study of the Iranian version. Eastern Mediterranean Health J 11(3):349–357 Motamed N, Ayatollahi AR, Zare N, Sadeghi-Hassanabadi A (2005) Validity and reliability of the Persian translation of the SF-36 version 2 questionnaire. Springer, Netherlands, Dordrecht, pp 5939–5940 In: Michalos AC (ed) Encyclopedia of quality of life and well-being research. Jalali MM, Gerami H, Saberi A, Razaghi S (2020) The Impact of Betahistine versus dimenhydrinate in the resolution of residual dizziness in patients with benign paroxysmal positional vertigo: a randomized clinical trial. Seok JI, Lee HM, Yoo JH, Lee DK (2008) Residual dizziness after successful repositioning treatment in patients with benign paroxysmal positional vertigo. İnan HC, Kıraç M (2019) An Evaluation of the Effects of Betahistine and Dimenhydrinate on Posterior Canal Benign Paroxysmal Positional Vertigo. Sayin I, Koç RH, Temirbekov D, Gunes S, Cirak M, Yazici ZM (2022) Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial. Benign paroxysmal positional vertigo in emergency department: How to treat? Hong Kong J Emer Med 1024907920972283 Gulen M, Satar S, Acehan S, Avci A, Kaya A, Sener K, et al. Hui J, Lei Q, Ji Z, Zi D (2022) Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway. Helminski JO, Zee DS, Janssen I, Hain TC (2010) Effectiveness of particle repositioning maneuvers in the treatment of benign paroxysmal positional vertigo: a systematic review. Hashami L, Haj Mohamad Ebrahim Ketabforoush A, Nirouei M (2022) Giant cell arteritis with rare manifestations of stroke and internal carotid artery dissection: a case study. Ravandi F, Haj Mohamad Ebrahim Ketabforoush A, Azedi F, Hoshyarkhani M, Fayyaz F, Abbasi Khoshsirat N (2022) Heart failure status among acute ischemic stroke patients: a hospital-based study. Lee JD, Shim DB, Park HJ, Song CI, Kim M-B, Kim C-H et al (2014) A multicenter randomized double-blind study: comparison of the Epley, Semont, and sham maneuvers for the treatment of posterior canal benign paroxysmal positional vertigo. In severe forms of BPPV, betahistine or dimenhydrinate might effectively reduce the symptoms. Older patients in the betahistine group had better social activities after treatment ( P = 0.048). There were significant differences between the females and males in emotional well-being before and after treatment in the dimenhydrinate group ( P = 0.014) and in terms of role limitation due to physical health problems in the Epley maneuver group ( P = 0.022). There was a marginally significant difference between the betahistine and dimenhydrinate groups in role limitation due to physical health problems ( P = 0.046). There was no significant difference between the groups in age ( P = 0.753) and gender ( P = 0.050).There were significant differences in all areas of SF-36 except for social activities in the dimenhydrinate group. SF-36 and the DHI were used before and after the treatment. Patients received betahistine 8 mg TDS or dimenhydrinate 50 mg once daily plus Epley or the Epley alone for four weeks. 90 adult patients diagnosed with BPPV in hospitals and ENT clinics were selected through convenience sampling. This prospective cohort study was performed in Mashhad, Iran, from 2013 to 2015. This study was designed to compare betahistine and dimenhydrinate plus the Epley maneuver and the Epley maneuver alone. Although the Epley maneuver is considered the primary treatment in BPPV, anti-vertigo medications are effective in residual symptoms.
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